Supartz is approved for treatment of knee osteoarthritis. Supartz is a non- surgical, non-pharmacologic therapy, the treatment can improve mobility and relieve pain for knee osteoarthritis. Supartz is ideal for patients who failed conservative treatments, including physical therapy and exercise. Supartz contains highly purified sodium hyaluronate (hyaluronic acid) which is extracted from chicken cobs. Supartz is injected once a week, for 5 weeks. Some patients may already have a good response to after 3 weeks. The injection may work as a lubricant and shock absorber in the affected joint.