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Cingal
CINGAL® is a powerful single injection treatment for the pain of osteoarthritis. CINGAL® is the first approved combination of viscosupplement that combines proven benefits of a proprietary hyaluronic acid (HA) with a well-established steroid to provide fast acting and long lasting pain relief from osteoarthritis.
When you have osteoarthritis, there may not be enough natural hyaluronan in the joint, and the quality of the hyaluronan may be poorer than normal. By injecting CINGAL®, a higher concentration of HA is achieved, which in conjunction with the steroid helps to reduce pain and improve joint mobility. CINGAL® is given in one single injection directly into the knee joint, where it acts as a lubricant and shock absorber. The product provides long long lasting pain relief and is proven to last up to 6 months.
CINGAL PROVIDES SHORT-TERM AND LONG-LASTING PAIN RELIEF
CINGAL® is a unique single-injection treatment that is proven to safely and effectively treat pain and certain symptoms associated with osteoarthritis.
WHAT IS OSTEOARTHRITIS
Osteoarthritis (OA) is the most common form of chronic joint diseases, which affects millions of people worldwide. It tends to start in the 50s and can affect any joint, but most often, it occurs in knees, hips, hands and the lower back.
OA is caused by joint damage, where the protective cartilage and tissue around the joints are slowly destroyed, causing pain and swelling. Some people are not affected by osteoarthritis, while others experiences severe pain, where the disease affects both functionality, mobility and quality of life.
The main symptoms of osteoarthritis are joint pain and stiffness, which causes problems in moving the affected joint. Some people also have symptoms of swelling, tenderness or crackling sounds when moving the joint.
While there is no cure for OA, there is a number of treatment options that can be explored depending on the severity of osteoarthritis. The most common approaches to treat knee pain caused by OA is physical therapy, weight loss and regular exercise. Alternative treatment options could be viscosupplements such as Hyaluronic acid or steroids as well as surgery in cases of knee replacements.
HOW DOES CINGAL® WORK?
In a normal joint, the articular cartilage acts as a protection for the ends of the bones that rub against each other. In a joint with osteoarthritis, the articular cartilage loses its smooth surface and instead becomes irregular and frayed.
Joints affected by osteoarthritis does typically have a lower concentration of hyaluronic acid in the synovial fluid that surrounds the joints. The synovial fluid is a thick liquid that helps to cushion and lubricate the joint. In cases of osteoarthritis, the amount of natural hyaluronan is reduced and the quality may be poorer than normal, which causes irritation, inflammation, pain and stiffness in the joints.
When CINGAL® is injected it helps to add a high concentration of cross-linked Hyaluronic acid (HA) to the joint, which acts as a lubricant and shock absorber, while the triamcinolone hexacetonide (steroid) reduces the inflammation and provides fast short-terms pain relief. Furthermore, HA helps to improve the elasticity and function of the joint as well protect the surface of the articular cartilage.
HOW LONG DOES THE RESULT LAST?
CINGAL® only requires a single injection to achieve fast acting and long lasting pain relief that is proven to last up to 6 months. Some patients experience pain relief for longer than 6 months.
